Researchers are developing a groundbreaking approach to fight cancer by using bacteria that consume tumors from the inside out. The method utilizes a soil bacterium called Clostridium sporogenes, which thrives in the oxygen-deprived cores of solid tumors, effectively breaking them down.
To prevent the bacteria from dying when exposed to oxygen near the tumor’s edge, scientists modified them with special genes. They created a “DNA circuit” that allows the bacteria to adapt and survive longer, ensuring they can destroy the cancer more effectively without harming healthy tissue.
This innovative bio-engineering, described in the journal ACS Synthetic Biology, is currently moving towards pre-clinical trials. It represents a promising new frontier in medical science, potentially offering a targeted therapy for difficult-to-treat cancers .
Scientists Engineer Bacteria to Devour Cancer Tumors from Within
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