Police in Nangarhar reported a massive fire sweeping through the timber market in Jalalabad city early Tuesday morning.
The blaze, caused by an electrical short circuit, has resulted in significant financial losses for local merchants.
While no casualties were reported, millions of Afghanis worth of inventory were reduced to ashes.
Firefighters managed to contain the flames, but not before substantial damage was inflicted on the businesses.
Fires in Afghan markets are a recurring issue, often blamed on poor safety standards and faulty wiring.
Authorities are still assessing the precise extent of the financial destruction caused by this latest incident.