Ali Khamenei has dismissed ongoing protesters as “rioters” and threatened a security crackdown.
Speaking on Friday, he claimed the unrest serves the interests of US President Donald Trump and aims to destabilize the country.
Meanwhile, Trump has warned of military strikes if Iranian security forces kill demonstrators.
The nationwide protests calling for the fall of the religious government have now entered their thirteenth consecutive day.
Human rights groups report at least 45 deaths and over a hundred injuries so far.
NetBlocks has also confirmed significant internet disruptions across Iran for the past 12 hours, signaling an information blackout.
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